
<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/">
  <dc:description xml:lang="srp">Cilj: Koronarna angiografija pomoću kompjuterizovane tomografije (MSCT)
omogućava uvid u morfološke karakteristike koronarne okluzivne bolesti, ali sa
otežanom preciznom kvantifikacijom aterosklerotskih lezija. Transtorakalna
Doppler ehokardiografija (TTDE) procenjuje funkcionalni značaj
aterosklerotskih lezija. Tokom studije smo pokušali da procenimo aditivni
dijagnostički i prognostički značaj koronarne rezerve protoka (CFR) određene
putem TTDE kod bolesnika sa prethodno detektovanim aterosklerotskim
lezijama putem MSCT na prednje descedentoj arteriji (LAD) i desnoj koronaroj
arteriji (RCA), koristeći invazivnu koronarografiju (IK) kao referenti metod.
Metode: Prospektivna studija je obuhvatila 84 bolesnika, u stabilnom
kardijalnom statusu, sa prethodno verfikovanim koronarnim stenozama na LAD
i/ili RCA putem MSCT. TTDE procena CFR-a sa adenozinom je izvršena na LAD
(n=75); RCA (n=61), ukupno 136 arterija, IK je sprovedena kod svih bolesnika
24 do 48 sati posle TTDE-CFR-a.
Rezultati: Analiza Cochran Q testom je uočila statistički značajnu razliku
između tehnika pri detekciji signifikantnih stenoza na LAD i RCA (p&lt;0.01),
analiza između pojedinačnih tehnika je pokazala značajnu razliku između
MSCT-a i C FR-a (p&lt;0.05), MSCT-a i IK (p&lt;0.01), dok između CFR-a i I K n ije
detektovana značajna razlika (p&gt;0.05). MSCT je imala senzitivnost za
LAD:88.00%; RCA:86.21, specifičnost LAD:57.63%; RCA:69.10%, pozitivna
LAD:46.81%; RCA:59.52% i negativna predikativna vrednost LAD:91.19%;
RCA:90.48%, dijagnostička pouzdanost LAD:66.67%; RCA:75.00% pri detekciji signifikatnih stenoza...</dc:description>
  <dc:description xml:lang="eng">Purpose: Multi-slice computed coronary angiography (MSCT) provides
morphological information about coronary artery disease, but precise
quantification of stenosis remains difficult. Transthoracic color Doppler
Echocardiography (TDE) gives insight into the functional significance of
coronary stenosis. We have tried to assess the additive diagnostic and
prognostic value of coronary flow reserve (CFR) determined by TDE over MSCT
in prediction of significant stenosis on the left anterior descending artery (LAD)
and right coronary artery (RCA) using invasive coronary angiography (ICA) as
reference method.
Methods: This prospective study included 84 patients, in stable cardiac status,
with previously detected atherosclerotic lesions on LAD and/or RCA by MSCT.
CFR assessment by TDE with adenosine was obtained in LAD (n=75); RCA
(n=61), resulting in 136 vessels for analysis. ICA was preformed to all 24 to 48
hours after CFR.
Results: Cochrans Q test found a significant statistical difference between
these techniques in detection of a significant stenosis on LAD and RCA
(p&lt;0.01), further analyzes revealed a significant difference between MSCT and
CFR (p&lt;0.05), MSCT and ICA (p&lt;0.01), while between CFR and ICA we didn’t
find a significant difference (p&gt;0.05). MSCT had sensitivity LAD:88.00%;
RCA:86.21, specificity LAD:57.63%; RCA:69.10%, positive LAD:46.81%;
RCA:59.52% and negative predictive value LAD:91.19%; RCA:90.48%,
diagnostic accuracy LAD:66.67%; RCA:75.00% in detection of significant
stenosis. When the results of both methods were agreed diagnostic accuracy was improved LAD 97.33%; RCA 90.00%.</dc:description>
  <dc:description xml:lang="srp">Kardiologija - Neinvazivna kardiološka dijagnostika / Cardiology - Noninvasive diagnostic of cardiology 
Datum odbrane : 01.04.2013 </dc:description>
  <dc:contributor>Đorđević-Dikić, Ana, 1964-</dc:contributor>
  <dc:contributor>Šobić-Šaranović, Dragana, 1962-</dc:contributor>
  <dc:contributor>Beleslin, Branko, 1964-</dc:contributor>
  <dc:contributor>Matić, Danica</dc:contributor>
  <dc:type>info:eu-repo/semantics/bachelorThesis</dc:type>
  <dc:identifier>https://phaidrabg.bg.ac.rs/o:7067</dc:identifier>
  <dc:identifier>cobiss:44694799</dc:identifier>
  <dc:identifier>thesis:761</dc:identifier>
  <dc:creator>Mladenović, Zorica T., 1977-</dc:creator>
  <dc:language>srp</dc:language>
  <dc:date>2012</dc:date>
  <dc:subject xml:lang="srp">OSNO - Opšta sistematizacija naučnih oblasti, Kardiologija</dc:subject>
  <dc:subject xml:lang="eng">OSNO - Opšta sistematizacija naučnih oblasti, Kardiologija</dc:subject>
  <dc:subject xml:lang="srp">neinvazivna dijagnostika, koronarna okluzivna bolest, koronarnarezerva protoka, Koronarna angiografija pomoću kompjuterizovane tomografije</dc:subject>
  <dc:subject xml:lang="eng">non invasive diagnostic, coronary artery disease, coronary flowreserve, multi-slice computed coronary angiography</dc:subject>
  <dc:subject xml:lang="srp">616.1</dc:subject>
  <dc:rights>http://creativecommons.org/licenses/by/2.0/at/legalcode</dc:rights>
  <dc:format>PDF/A (97 listova)</dc:format>
  <dc:format>5338122 bytes</dc:format>
  <dc:title xml:lang="srp">Dijagnostički i prognostički značaj procene koronarne rezerve protoka određene transtorakalnom Doppler ehokardiografijom kod bolesnika sa urađenom koronarnom angiografijom pomoću kompjuterizovane tomografije  : doktorska disertacija</dc:title>
</oai_dc:dc>