eng https://phaidrabg.bg.ac.rs/o:39513 ISBN: 978-86-82679-17-2 http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode Bioinformatics identification of extracellular vesicle-derived microRNAs biomarkers in pancreatic cancer Extracellular vesicles, microRNA, Pancreatic cancer Institut za molekularnu genetiku i genetičko inženjerstvo, Univerzitet u Beogradu, Beograd, Srbija 6th Belgrade Bioinformatics Conference-Book of Abstracts ABSTRACT Pancreatic cancer is one of the most lethal malignancies worldwide due to the lack of effective early diagnostic tools and its asymptomatic early stages. It is the 6th leading cause of cancer-related mortality, with a 5-year survival rate ranging from 44% in localized disease to 3% in metastatic cases. CA19-9, the most commonly used biomarker, has limited sensitivity and low positive predictive value, restricting its use in screening. Therefore, novel biomarkers are needed, and extracellular vesicle-associated miRNAs (EV-miRNAs) are increasingly recognized for their stability and potential in non-invasive cancer diagnosis. 2026 Goč, Sanja Dobrijević, Zorana Janković, Tamara Janjić, Filip Mitić, Ninoslav Janković, Miroslava info:eu-repo/semantics/conferenceProceedings application/pdf 3358377 bytes