o:37163 Noncoding RNAs as biomarkers of gestational diabetes mellitus en Non-coding RNAs (ncRNAs), including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), show potential to serve as biomarkers of metabolic disorders, oxidative stress and inflammatory status, and thus may have diagnostic and prognostic significance in gestational diabetes mellitus (GDM). Aberrant expression of specific ncRNAs has been identified in placental tissue, plasma, serum, extracellular vesicles, peripheral blood mononuclear cells (PBMCs), as well as in other maternal and fetal sources. These ncRNAs exhibit high stability in circulation and can reflect underlying molecular alterations, making them promising non-invasive biomarkers for diagnosis, prognosis, and disease monitoring. Therefore, this article will review the major findings of GDM-related ncRNAs and highlight their potential role in improving clinical outcomes through biomarker-based approaches. gestational diabetes mellitus, miRNA, lncRNA, circRNA, liquid biopsy 1552101 2787-2947 2025-12-01T10:17:42.937Z 44 yes 46 Jovana Stevanović University of Belgrade, Institute for the Application of Nuclear Energy, Serbia master biolog 0000-0002-3619-8472 Zorana Dobrijević University of Belgrade, Institute for the Application of Nuclear Energy INEP, Serbia doktor bioloških nauka person 0000-0002-4652-7719 application/pdf 993047 https://phaidrabg.bg.ac.rs/o:37163 no yes 16 70 1556235 11A29 11A2905 Noncoding RNAs as biomarkers of gestational diabetes mellitus 5 22 38 Trendovi u molekularnoj biologiji (Trends in Molecular Biology)) Beograd, Srbija Institut za molekularnu genetiku i genetičko inženjerstvo 2025