o:36695 New Emerging Avian Virus – Bornavirus Origin and Epidemiology en Numerous genomes of avian bornaviruses were identified in 2008 as significant pathogens for various species of waterfowl and parrots. Previously, during the 1970s, bornaviruses had been recognized as the cause of several epidemics, although it is unclear whether these incidents were directly related to avian bornavirus (ABV), given the differences in pathological lesions observed in parrots and waterfowl. The identification of ABV also resolved the cause of proventricular dilatation disease (PDD), a fatal condition affecting the neurological and gastrointestinal systems of birds. Epidemiological studies in Germany have confirmed the presence of this virus in both wild and captive birds, highlighting its widespread nature and zoonotic potential. Diagnosis of PDD is performed using immunohistochemical methods and RT-PCR testing of tissue samples from deceased birds. However, detecting the virus in living birds is challenging due to the possibility of false-positive results in healthy carriers and intermittent shedding of the virus in infected ones, leading to false-negative findings. Research also indicates the limitations of serological methods, which fail to effectively distinguish between infected birds and healthy carriers of the virus. Additionally, the significant potential zoonotic risk of bornaviruses is emphasized, particularly given their ability to cross species barriers. Although there are currently no documented cases of transmission to humans, the genetic similarity between avian and mammalian strains of bornaviruses suggests a potential danger to humans, necessitating further research and the development of preventive strategies to minimize the risk of zoonoses. Avian bornavirus, Epidemiology, Diagnostic challenges, PDD 1552100 978-99976-186-2-7 2025-10-08T11:42:38.896Z 44 yes 46 Nemanja Krstić University of Belgrade, Institute for the Application of Nuclear Energy, Serbia Doktor veterinarske medicine 0000-0002-5641-964X Dragan Kasagic Veterinary Institute of the Republic of Srpska “Dr. Vaso Butozan” Banja Luka, Banja Luka, Bosnia and Herzegovina person Marija Gnjatović University of Belgrade, Institute for the Application of Nuclear Energy, Serbia doktor tehnoloških nauka person 0000-0001-8233-1636 application/pdf 2683924 https://phaidrabg.bg.ac.rs/o:36695 no yes 19 70 92000004 11A29 11A2910 New Emerging Avian Virus – Bornavirus Origin and Epidemiology 22 Abstarct Book, 29. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (BiH) Veterinarska komora Republike Srpske, BiH 2024