o:36535 Correlation between the expression of proinflammatory cytokine genes and immunomodulatory microRNAs miR-27a, miR-222 and miR-340 in peripheral blood mononuclear cells of women with gestational diabetes en ABSTRACT Continuous low-level inflammation (IFM) is a major contributory factor to development of severe pregnancy complications associated with gestational diabetes mellitus (GDM). Presence of IFM throughout the hyperglycemic pregnancy associates with disturbances in microRNA-related mechanisms, while inflammatory pathway-related genes are known targets of microRNAs dysregulated in GDM. Our aim was to evaluate the correlation between the expression of GDM related microRNAs (miR-27a, miR-222 and miR-340) and mRNA encoding proinflammatory cytokines IL-1β, IL-8, TNFα and IL6 in peripheral blood mononuclear cells (PBMCs) from women with GDM and healthy controls. IL-1β, IL-8, IL-6, TNFα, miRNA 1552100 978-86-82679-18-9 1552102 https://imagine.imgge.bg.ac.rs/bitstream/handle/123456789/3006/bitstream_847505.pdf?sequence=1&isAllowed=y 2025-09-08T09:03:16.765Z 44 yes 46 Jovana Stevanović University of Belgrade, Institute for the Application of Nuclear Energy INEP, Serbia 0000-0002-3619-8472 Iva Vasiljević University of Belgrade-Faculty of Biology, Belgrade, Serbia person Ognjen Radojičić Gynecology and Obstetrics Clinic "Narodni front", Belgrade, Serbia person Milica Mandić Gynecology and Obstetrics Clinic "Narodni front", Belgrade, Serbia person Dragana Maglić Gynecology and Obstetrics Clinic "Narodni front", Belgrade, Serbia person Vesna Mandić-Marković Gynecology and Obstetrics Clinic "Narodni front", Belgrade, Serbia person Željko Miković University of Belgrade-Faculty of Medicine, Belgrade, Serbia person Olgica Nedić University of Belgrade, Institute for the Application of Nuclear Energy INEP, Serbia doktor biohemijskih nauka person 0000-0003-2042-0056 Zorana Dobrijević University of Belgrade, Institute for the Application of Nuclear Energy INEP, Serbia doktor bioloških nauka person 0000-0002-4652-7719 application/pdf 496672 https://phaidrabg.bg.ac.rs/o:36535 no yes 16 70 92000004 11A29 11A2905 11A02 11A32 Abstract Book-BeCELS 2025: Belgrade Conference for Early-Career Life Scientists Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Serbia 2025