Stevanović, Jovana Vasiljević, Iva Radojičić, Ognjen Mandić, Milica Maglić, Dragana Mandić-Marković, Vesna Miković, Željko Nedić, Olgica Dobrijević, Zorana IL-1β, IL-8, IL-6, TNFα, miRNA https://phaidrabg.bg.ac.rs/o:36535 ISBN: 978-86-82679-18-9 info:eu-repo/semantics/conferenceProceedings 2025 eng Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Serbia application/pdf 496672 bytes ABSTRACT Continuous low-level inflammation (IFM) is a major contributory factor to development of severe pregnancy complications associated with gestational diabetes mellitus (GDM). Presence of IFM throughout the hyperglycemic pregnancy associates with disturbances in microRNA-related mechanisms, while inflammatory pathway-related genes are known targets of microRNAs dysregulated in GDM. Our aim was to evaluate the correlation between the expression of GDM related microRNAs (miR-27a, miR-222 and miR-340) and mRNA encoding proinflammatory cytokines IL-1β, IL-8, TNFα and IL6 in peripheral blood mononuclear cells (PBMCs) from women with GDM and healthy controls. http://creativecommons.org/licenses/by/4.0/legalcode Abstract Book-BeCELS 2025: Belgrade Conference for Early-Career Life Scientists Correlation between the expression of proinflammatory cytokine genes and immunomodulatory microRNAs miR-27a, miR-222 and miR-340 in peripheral blood mononuclear cells of women with gestational diabetes