Stevanović, Jovana Mitić, Ninoslav Penezić, Ana Radojičić, Ognjen Ardalić, Daniela Mandić, Milica Mandić-Marković, Vesna Miković, Željko Brkušanin, Miloš Nedić, Olgica Dobrijević, Zorana International Journal of Molecular Sciences volume: 26 number: 14 startpage: 6902 application/pdf 3429421 bytes 2025 ABSTRACT MicroRNA-based regulatory mechanisms show disturbances related to oxidative stress (OS) interconnected with inflammation (IFM), as well as impairments associated with gestational diabetes (GDM). The aim of this study was to assess the diagnostic and prognostic significance of the OS/IFM-related microRNA in GDM by using peripheral blood mononuclear cells (PBMCs) and serum-derived extracellular vesicles (EVs) as biological samples. We selected the known OS/IFM-associated microRNAs miR-146a-5p, miR-155-5p, and miR-21-5p as candidates for our GDM biomarker analysis. https://phaidrabg.bg.ac.rs/o:36449 doi:10.3390/ijms26146902 info:eu-repo/semantics/article eng http://creativecommons.org/licenses/by/4.0/legalcode miR-21-5p; miR-155-5p; miR-146a-5p; oxidative stress; redox status; gestational diabetes; iron; superoxide dismutase; adverse outcomes MDPI, Basel, Switzerland Upregulation of the Antioxidant Response-Related microRNAs miR-146a-5p and miR-21-5p in Gestational Diabetes: An Analysis of Matched Samples of Extracellular Vesicles and PBMCs