o:36342 UV irradiation influence on fumitory extract-loaded liposomes en The aim of the present study was the characterization of fumitory extract-loaded liposomal vesicles after UV irradiation via the determination of the encapsulation efficiency, size, polydispersity index (PDI), zeta potential, mobility, and conductivity. The encapsulation efficiency was the same before and after UV irradiation (>69%). The particle size and PDI of the UV-irradiated liposomes with the fumitory extract were 294.2 ± 4.1 nm and 0.387 ± 0.011, respectively. The zeta potential after UV irradiation was −5.51 ± 0.4 mV. The mobility and conductivity of the obtained liposomal particles were −0.429 ± 0.012 µmcm/Vs and 0.468 ± 0.005 mS/cm, respectively. The results indicate the existence of nanoparticles and a non-uniform system, while a negative zeta potential value is related to the organization of phospholipids. Since UV irradiation did not cause significant changes in all of the mentioned parameters of the fumitory extract-loaded liposomes, it can be employed as a sterilization step in the preparation of liposomes. Fumaria officinalis; liposomes; particle size; UV irradiation; zeta potential 1552099 https://doi.org/10.3390/engproc2025099016 2025-06-18T17:00:08.347Z 44 yes 46 Rabiea Ahmoda Faculty of Technology and Metallurgy, University of Belgrade Andrea Pirković Institute for the Application of Nuclear Energy INEP, University of Belgrade, Serbia doktor bioloških nauka person 0000-0002-1182-4895 Milena Milošević Institute of Chemistry, Technology and Metallurgy—National Institute of the Republic of Serbia, University of Belgrade, Serbia person Aleksandar Marinkovic Faculty of Technology and Metallurgy, University of Belgrade person Aleksandra Jovanović Institute for the Application of Nuclear Energy INEP, University of Belgrade, Banatska 31b, 11080 Belgrade, Serbia doktor tehnoloških nauka person 0000-0001-5394-0125 application/pdf 190908 https://phaidrabg.bg.ac.rs/o:36342 no yes 16 70 92000004 11A24 11A29 11A41 UV irradiation influence on fumitory extract-loaded liposomes 99 1 16 Engineering Proceedings Basel, Switzerland MDPI 2025