http://creativecommons.org/licenses/by/4.0/legalcode info:eu-repo/semantics/article White, Ruby Sotillo, Javier Ancarola, María Eugenia Borup, Anne Toftegaard Boysen, Anders Brindley, Paul J. Buzás, Edit I. Cavallero, Serena , et al. Kosanović, Maja Special considerations for studies of extracellular vesicles from parasitic helminths: A community-led roadmap to increase rigour and reproducibility electron microscopy, EV guidelines, EV reporting, extracellular vesicles, helminths, parasites https://phaidrabg.bg.ac.rs/o:36244 doi:10.1002/jev2.12298 application/pdf 5097154 bytes 2023 Wiley Periodicals, LLC on behalf of the International Society for Extracellular Vesicles Journal of Extracellular Vesicles volume: 12 number: 1 ABSTRACT Over the last decade, research interest in defining how extracellular vesicles (EVs) shape cross-species communication has grown rapidly. Parasitic helminths, worm species found in the phyla Nematoda and Platyhelminthes, are well-recognised manipulators of host immune function and physiology. Emerging evidence supports a role for helminth-derived EVs in these processes and highlights EVs as an important participant in cross-phylum communication. While the mammalian EV field is guided by a community-agreed framework for studying EVs derived from model organisms or cell systems [e.g., Minimal Information for Studies of Extracellular Vesicles (MISEV)], the helminth community requires a supplementary set of principles due to the additional challenges that accompany working with such divergent organisms. eng