o:36207 Stability of Cotinus coggygria Scop. Extract-Loaded Liposomes: The Impact of Storage on Physical and Antioxidant Properties en The stability of Cotinus coggygria extract-loaded liposomes (non-treated and UV irradiated) was determined after 60 days through an investigation of the impact of storage on liposomal physical and antioxidant properties. The liposome size varied in a narrow range for 60 days; PDI was 0.273–0.313 (non-treated) and 0.829–0.911 (UV-irradiated). The zeta potential ranged from −28.2 to −29.6 mV (non-treated) and from −21.5 to −22.0 mV (UV-irradiated). The obtained liposomes with the extract neutralized 81.9% of free DPPH radicals before UV irradiation and 80.9% after irradiation. In the ABTS assay, UV irradiation also significantly reduced the antioxidant capacity, from 12.02 to 10.55 µmol Trolox equivalent (TE)/mL. The ABTS and DPPH radical scavenging activity of the UV-irradiated liposomes significantly decreased after the 60-day storage (8.93 µmol TE/mL and 75.4%, respectively), whereas in the non-treated sample, the mentioned drop in antioxidant capacity was not noticed. Liposomal formulations of C. coggygria extract can exhibit significant potential for further development as a functional food or dermo-cosmetic ingredient. liposomes; storage stability; antioxidant capacity; Cotinus coggygria; extract 1552099 10.3390/proceedings2025119004 2025-05-28T09:52:35.782Z 44 yes 46 Aleksandra A. Jovanović University of Belgrade, Institute for the Application of Nuclear Energy, Serbia doktor tehnoloških nauka 0000-0001-5394-0125 Amjed Karkad University of Belgrade, Faculty of Technology and Metallurgy, Karnegijeva 4, Belgrade, Serbia person Andrea Pirković University of Belgrade, Institute for the Application of Nuclear Energy INEP, Serbia doktor bioloških nauka person 0000-0002-1182-4895 Dragana Dekanski University of Belgrade, Institute for the Application of Nuclear Energy INEP, Serbia doktor medicinskih nauka person 0000-0001-8467-4165 Diana Lupulović University of Belgrade, Institute for the Application of Nuclear Energy INEP, Serbia doktor veterinarskih nauka person 0000-0002-2476-4887 Miroslav Novaković University of Belgrade, Institute of Chemistry, Technology and Metallurgy, Belgrade, Serbia person Aleksandar Marinkovic University of Belgrade, Faculty of Technology and Metallurgy, Serbia person application/pdf 213809 https://phaidrabg.bg.ac.rs/o:36207 no yes 16 70 92000004 11A29 11A24 11A41 Stability of Cotinus coggygria Scop. Extract-Loaded Liposomes: The Impact of Storage on Physical and Antioxidant Properties 119 119 1 4 Proceedings Basel, Switzerland MDPI 2025