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    <ns1:title language="en">Intranasal application of Trichinella spiralis muscle larvae extracellular vesicles alleviate inflammation in mouse model of respiratory allergy</ns1:title>
    <ns1:language>en</ns1:language>
    <ns1:description language="en">ABSTRACT
Introduction: The parasitic helminth, the nematode Trichinella spiralis, affects the host immune system through its excretory-secretory products (ES L1), which contain extracellular vesicles (EVs) that prevent host immune response to itself and also the development of chronic inflammatory diseases in the host. EVs from T. spiralis muscle larvae (TsEVs) have been shown to exert immunomodulatory properties on human dendritic cells, inducing a stable tolerogenic phenotype and eliciting regulatory T cells (Treg). Furthermore, it has been shown that infection with T. spiralis can alleviate allergic airway inflammation in mice. Therefore, the aim of this work was to investigate whether TsEVs alone have the same effect.</ns1:description>
    <ns1:keyword language="en">extracellular vesicles, Trichinella spiralis</ns1:keyword>
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        <ns3:firstname>Sofija</ns3:firstname>
        <ns3:lastname>Glamočlija</ns3:lastname>
        <ns3:institution>University of Belgrade, Institute for the Application of Nuclear Energy INEP, Serbia</ns3:institution>
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    <ns12:publisher>Serbian Society for Extracellular Vesicles, SrbEVs with Austrian Society for Extracellular Vesicles, ASEV Baltic Society for Extracellular Vesicles, BSEV Italian Society for Extracellular Vesicles, EVIta French Society for Extracellular Vesicles, FSEV Spanish Society for Extracellular Vesicles, GEIVEX German Society for Extracellular Vesicles, GSEV United Kingdom Society for Extracellular Vesicles, UKEV</ns12:publisher>
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