eng application/pdf 96677 bytes TsEVs, autoimmune diseases, extracellular vesicles, Trichinella spiralis Journal of extracellular vesicles/ISEV2021 Annual Meeting, May 18-21, 2021, Virtual meeting-ISEV2021 Abstract Book volume: 10 (Suppl 1) ABSTRACT Excretory-secretory products (ES) of parasitic worms (helminths) shift hosts’ immunological balance toward Th2 and regulatory responses thus acting beneficial in chronic inflammations, i.e. autoimmune diseases. As shown in several helminths, extracellular vesicles (EVs) are active immunomodulatory component of ES.We found that Trichinella spiralis produces EVs (TsEVs) which influence cytokine production by PBMC. Now we aim to show how TsEVs influence human dendritic cells (DC), as key players in initiation, progression and regulation of immune response. Wiley Periodicals, LLC on behalf of the International Society for Extracellular Vesicles https://phaidrabg.bg.ac.rs/o:35967 doi:10.1002/jev2.12083 ISSN: 2001-3078 Immunomodulation by extracellular vesicles from Trichinella spiralis muscle larvae: increasing tolerogenic properties of human dendritic cells Glamočlija, Sofija Kosanović, Maja Sofronić-Milosavljević, Ljiljana Tomić, Sergej Sabljić, Ljiljana Gruden-Movsesijan, Alisa Ilić, Nataša 2021 http://creativecommons.org/licenses/by/4.0/legalcode info:eu-repo/semantics/conferenceProceedings