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    <ns1:title language="en">ETS1 Protein Expression May Be Altered by the Complementarity of ETS1 mRNA Sequences with miR-203a-3p and miR-204-3p in Papillary Thyroid Carcinoma</ns1:title>
    <ns2:alt_title language="sr">Komplementarnost sekvenci ETS1 iRNK sa miR-203a-3p i miR-204-3p može uticati na ekspresiju ETS1 proteina u papilarnom karcinomu štitaste žlezde</ns2:alt_title>
    <ns1:language>en</ns1:language>
    <ns1:description language="en">ABSTRACT
The expressions of ETS1, miR-203a-3p, and miR-204-3p in papillary thyroid carcinoma (PTC) are poorly described, and their clinical significance is unclear. To determine the prognostic value of ETS1 (E26 transformation-specific), its levels in divergent cell
compartments were paired with miR-203a-3p/-204-3p levels and linked to the presence of
unfavorable clinical characteristics of PTC patients. Immunohistochemistry and Western blot were performed to evaluate ETS1 protein expression in PTC and matched nonmalignant thyroid tissue (NMT). qPCR was utilized to quantify ETS1 mRNA, miR-203a-3p, and miR-204-3p expressions. Bioinformatic analysis was applied to predict biological interactions. </ns1:description>
    <ns1:keyword language="en">PTC; miRNA; cancer biomarker; prognostic factor; microRNA; subcellular localization</ns1:keyword>
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      <ns2:resource>1552099</ns2:resource>
      <ns2:identifier>10.3390/ijms26031253 </ns2:identifier>
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        <ns3:firstname>Stefana</ns3:firstname>
        <ns3:lastname>Stojanović Novković</ns3:lastname>
        <ns3:institution>University of Belgrade, Institute for the Application of Nuclear Energy INEP, Belgrade, Serbia</ns3:institution>
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        <ns3:firstname>Marija</ns3:firstname>
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    <ns12:name_magazine language="en">International Journal of Molecular Sciences</ns12:name_magazine>
    <ns12:volume>26</ns12:volume>
    <ns12:booklet>3</ns12:booklet>
    <ns12:publisher>MDPI, Basel, Switzerland</ns12:publisher>
    <ns12:releaseyear>2025</ns12:releaseyear>
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