2024 University of Novi Sad-Institute of Food Technology in Novi Sad, Serbia Standardized black chokeberry (Aronia melanocarpa L.) extract supplementation lowers the salivary ROS levels in patients with oral lichen planus Aronia melanocarpa; saliva; oral lichen planus; ROS https://phaidrabg.bg.ac.rs/o:35280 doi:10.46793/8FDSQ.PD8AP info:eu-repo/semantics/article http://creativecommons.org/licenses/by-nc-nd/4.0/legalcode ABSTRACT The oxidative stress has a role in etiopathogenesis of oral lichen planus (OLP). Polyphenols renowned for their antioxidative, anti-inflammatory and immunomodulatory properties, have gained attention in autoimmune diseases management. Saliva, reflecting salivary gland health, offers promise for biomarker research and treatment monitoring. The aim of this study was to evaluate salivary levels of reactive oxygen species (ROS) in OLP patients using polyphenol rich, standardized Aronia melanocarpa extract (SAE). The ROS values were compared in pre- and post-treatment and significant differences were found, indicating the decrease of ROS after four-week supplementation with SAE. The 8th Workshop on Food and Drug Safety and Quality, Vinča-2024-Proceedings startpage: 210 endpage: 213 application/pdf 272983 bytes Pirković, Andrea Bojić-Trbojević, Žanka Prokić, Marko Stanimirović, D. Hadži-Mihailović, M. Dekanski, Dragana eng