o:35263 RADICAL SCAVENGING POTENTIAL OF DIFFERENT TYPES OF LIPOSOME PARTICLES WITH ENCAPSULATED CAROB EXTRACT en Carob pulp extract contains bioactive phenolic compounds, making it a suitable functional food ingredient. This study aimed to investigate the radical scavenging potential of pure carob extract and different types of carob extract-loaded liposomes (multilamellar, UV-irradiated, and sonicated unilamellar vesicles). Their antioxidant capacity was measured by employing DPPH and ABTS assays. The encapsulation of carob extract within liposomes as well as UV irradiation and sonication did not cause a decrease in the anti-DPPH activity, however, the ABTS radical scavenging potential of pure extract was significantly lower compared to encapsulated counterparts. UV irradiation and sonication significantly decreased the anti-ABTS effect of the liposome with the extract. Carob pulp extract and its liposomal formulations displayed significant in vitro antioxidant potential that can be of interest for further development as a functional food ingredient or in the prevention/treatment of various diseases. 1552100 978-86-7306-173-3 1552099 10.46793/8FDSQ.PA3DD 2024-11-29T20:50:38.154Z 44 yes 46 Dragana Dekanski Institute for the Application of Nuclear Energy INEP, University of Belgrade, Banatska 31b, 11080 Belgrade, Serbia doktor medicinskih nauka 0000-0001-8467-4165 Aleksandar Rašković Department of Pharmacology, Toxicology, and Clinical Pharmacology, Faculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia person Nikola Martić Department of Pharmacology, Toxicology, and Clinical Pharmacology, Faculty of Medicine, University of Novi Sad, 21000 Novi Sad, Serbia person Andrea Pirković Institute for the Application of Nuclear Energy INEP, University of Belgrade, Banatska 31b, 11080 Belgrade, Serbia doktor bioloških nauka person 0000-0002-1182-4895 Aleksandra Jovanović Institute for the Application of Nuclear Energy INEP, University of Belgrade, Banatska 31b, 11080 Belgrade, Serbia doktor tehnoloških nauka person 0000-0001-5394-0125 application/pdf 481568 https://phaidrabg.bg.ac.rs/o:35263 no yes 19 70 92000004 11A29 RADICAL SCAVENGING POTENTIAL OF DIFFERENT TYPES OF LIPOSOME PARTICLES WITH ENCAPSULATED CAROB EXTRACT 25 28 8 th Workshop FOOD AND DRUG SAFETY AND QUALITY September 26 th, 2024, PROCEEDINGS Vinča Institute of Nuclear Sciences-National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Republic of Serbia 2024