o:32252 Antioxidant activity of Paeonia tenuifolia L. petal extract-loaded liposomes en Steppe peony (Paeonia tenuifolia L., Paeoniaceae) is a perennial, herbaceous plant species which has been widely known for its medicinal use. This study is aimed at the development of P. tenuifolia petal dry methanolic extract-loaded liposomes and the determination of their antioxidant activity. The liposomes were prepared with three different phospholipid mixtures by the proliposome method. The antioxidant potential of the liposomes was assessed by the 2,2′-azino-bis(3-ethylbenzothiazoline-6- sulfonic acid) (ABTS•+) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging methods. The ABTS radical scavenging activity ranged from 66.99 to 69.15%, whereas for the DPPH, the values varied from 85.12 to 90.11%. These results revealed promising antioxidant activities of P. tenuifolia petal extract-loaded liposomes with the potential to be used for the treatment of health disorders associated with oxidative stress, such as skin-related problems. peony; antioxidant potential; liposomes; phospholipids; encapsulation 1552099 n https://doi.org/10.61652/leksir2343e167C 2024-01-09T12:53:21.813Z 44 yes 46 Natalija Čutović Institute for Medicinal Plants Research “Dr Josif Pančić”, Belgrade, Serbia Tatjana Marković Institute for Medicinal Plants Research “Dr Josif Pančić”, Belgrade, Serbia person Ana Zugic Institute for Medicinal Plants Research “Dr Josif Pančić”, Belgrade, Serbia person Petar Batinić Institute for Medicinal Plants Research “Dr Josif Pančić” Belgrade, Serbia person Branko Bugarski University of Belgrade, Faculty of Technology and Metallurgy, Serbia person Aleksandra Jovanović Institute for the Application of Nuclear Energy INEP, University of Belgrade, Serbia doktor nauka person 0000-0001-5394-0125 application/pdf 1036184 https://phaidrabg.bg.ac.rs/o:32252 no yes 19 70 1552253 11A41 11A29 Antioxidant activity of Paeonia tenuifolia L. petal extract-loaded liposomes e167 43 Lekovite sirovine 2023-12-25