Antioxidant activity of Paeonia tenuifolia L. petal extract-loaded liposomes http://creativecommons.org/licenses/by-nc-sa/4.0/legalcode https://phaidrabg.bg.ac.rs/o:32252 doi:n https://doi.org/10.61652/leksir2343e167C Steppe peony (Paeonia tenuifolia L., Paeoniaceae) is a perennial, herbaceous plant species which has been widely known for its medicinal use. This study is aimed at the development of P. tenuifolia petal dry methanolic extract-loaded liposomes and the determination of their antioxidant activity. The liposomes were prepared with three different phospholipid mixtures by the proliposome method. The antioxidant potential of the liposomes was assessed by the 2,2′-azino-bis(3-ethylbenzothiazoline-6- sulfonic acid) (ABTS•+) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging methods. The ABTS radical scavenging activity ranged from 66.99 to 69.15%, whereas for the DPPH, the values varied from 85.12 to 90.11%. These results revealed promising antioxidant activities of P. tenuifolia petal extract-loaded liposomes with the potential to be used for the treatment of health disorders associated with oxidative stress, such as skin-related problems. Antioxidant activity of Paeonia tenuifolia L. petal extract-loaded liposomes 43 Čutović, Natalija Marković, Tatjana Zugic, Ana Batinić, Petar Bugarski, Branko Jovanović, Aleksandra 2023-12-25 application/pdf 1036184 bytes info:eu-repo/semantics/article peony; antioxidant potential; liposomes; phospholipids; encapsulation eng