o:31707 The extraction of active compounds from plant waste: the potential in human and industrial applications as the concept of zero waste in the circular economy en ABSTRACT Plant waste contains various active compounds that can be applied in food, pharmaceutical, cosmetic, or other industries. Polyphenols, carotenoids, pectin, aromas, fibers, or enzymes extracted from agrifood waste can be considered ready-to-use without demanding and expensive downstream isolation and purification steps. In the present study, plant extracts were prepared using Thymus serpyllum and Vaccinium myrtillus leaf dust and empty Aloe vera leaves (the matrix without aloe gel). The biological potential of T. serpyllum, V. myrtillus, and A. vera waste extracts with the highest polyphenol yield was investigated. T. serpyllum extract possessed the highest DPPH radical scavenging capacity (1.50±0.02 mg/mL). It also had antimicrobial potential against all examined strains, particularly against Enterococcus faecalis, and showed spasmolytic activities in isolated rat ileum models of spontaneous contractions, acetylcholine- and potassium chloride-induced contractions. V. myrtillus extract showed the highest ABTS radical scavenging potential (48.77±1.47 µmol Trolox equivalents/g of plant material) and significant antimicrobial and skin regeneration activity (percentage of wound healing was 29.2±1.8). However, A. vera extract had the lowest antioxidant capacity and did not show antimicrobial potential, while it showed a significant wound healing influence (30.9±1.7%). Due to showed the biological potential of all prepared waste extracts, they can be potentially used in the food, pharmaceutical, and cosmetic industries. In future experiments, T. serpyllum waste extract will be examined in terms of bronchodilatory activity, whereas all prepared waste extracts will be investigated via effects on enzymes, dying of textile, as well as anticorrosive effects. biological activities, extraction, industrial potential, plant waste 1552100 978-86-6305-137-9 91552100 118723849 2023-11-20T08:20:58.670Z 44 yes 46 Aleksandra A. Jovanović University of Belgrade, Institute for the Application of Nuclear Energy INEP, Serbia doktor tehnoloških nauka 0000-0001-5394-0125 application/pdf 870462 https://phaidrabg.bg.ac.rs/o:31707 no yes 18 70 92000004 11A29 11A2910 Proceedings-30th International Conference-Ecological Truth and Environmental Research-EcoTER'23 7 17 University of Belgrade, Technical Faculty in Bor 2023