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  <ns1:general>
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    <ns1:title language="en">Aniticancer mechanisms of repurposed drugs in oncology on hamster model</ns1:title>
    <ns1:language>en</ns1:language>
    <ns1:description language="en">Abstract:
 Transcription factor NF-kB acts as an important target in oncology, as most of the molecules formed by transcription of genes trigger cancers. Also, ROS (Reactive Oxygen Species) activity is interconnected with NF-kB and cancer development. To identify NF-kB inhibition and/or ROS stimulation as antitumor mechanisms, we have screened combinations of currently approved non-oncological repurposed drugs that can inhibit hamster fibrosarcoma growth by rescuing cancer development with NF-kB stimulation and/or ROS inhibition.</ns1:description>
    <ns1:keyword language="en">Keywords : fibrosarcoma, hamsters, repurposed drugs, NF-kB, ROS.</ns1:keyword>
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      <ns2:resource>1552100</ns2:resource>
      <ns2:identifier>978-86-7197-742-5</ns2:identifier>
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      <ns2:resource>91552100</ns2:resource>
      <ns2:identifier>126492937</ns2:identifier>
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        <ns3:firstname>Kosta J.</ns3:firstname>
        <ns3:lastname>Popović</ns3:lastname>
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        <ns3:firstname>Dušica J.</ns3:firstname>
        <ns3:lastname>Popović</ns3:lastname>
        <ns3:institution>Državni univerzitet u Novom Pazaru</ns3:institution>
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        <ns3:orcid>0000-0001-7880-0874</ns3:orcid>
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        <ns3:firstname>Dejan</ns3:firstname>
        <ns3:lastname>Miljković </ns3:lastname>
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        <ns3:firstname>Dušan </ns3:firstname>
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        <ns3:orcid>0000-0002-0760-9180</ns3:orcid>
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        <ns3:firstname>Zana </ns3:firstname>
        <ns3:lastname>Dolićanin</ns3:lastname>
        <ns3:institution>Državni univerzitet u Novom Pazaru</ns3:institution>
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        <ns3:firstname>Ivan </ns3:firstname>
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        <ns3:orcid>0000-0001-7531-5099</ns3:orcid>
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        <ns3:firstname>Jovan K. </ns3:firstname>
        <ns3:lastname>Popović</ns3:lastname>        
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        <ns3:orcid>0000-0002-6790-8668</ns3:orcid>
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  <ns12:digitalbook>
    <ns12:name_magazine language="en">JCMST 2023 - The 2nd PSU-UNS Joint Conference on Medical Science and Technology, 11-13 October 2023</ns12:name_magazine>
    <ns12:booklet>2</ns12:booklet>
    <ns12:from_page>143</ns12:from_page>
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