info:eu-repo/semantics/conferenceProceedings Keywords : fibrosarcoma, hamsters, repurposed drugs, NF-kB, ROS. Abstract: Transcription factor NF-kB acts as an important target in oncology, as most of the molecules formed by transcription of genes trigger cancers. Also, ROS (Reactive Oxygen Species) activity is interconnected with NF-kB and cancer development. To identify NF-kB inhibition and/or ROS stimulation as antitumor mechanisms, we have screened combinations of currently approved non-oncological repurposed drugs that can inhibit hamster fibrosarcoma growth by rescuing cancer development with NF-kB stimulation and/or ROS inhibition. application/pdf 759473 bytes eng https://phaidrabg.bg.ac.rs/o:31329 cobiss:126492937 Aniticancer mechanisms of repurposed drugs in oncology on hamster model All rights reserved 2023 Popović, Kosta J. Popović, Dušica J. Miljković, Dejan Lalošević, Dušan Dolićanin, Zana Čapo, Ivan Popović, Jovan K. JCMST 2023 - The 2nd PSU-UNS Joint Conference on Medical Science and Technology, 11-13 October 2023(2)