application/pdf 2348126 bytes ABSTRACT The specter of malignant thyroid lesions comprises tumors with different degrees of differentiation, rendering the differential diagnosis and prognosis of these tumors challenging. Focal adhesion kinase (FAK) is a tyrosine kinase involved in cellular communication and locomotion, functioning as a hub in the interactome of focal adhesions. Its upregulation has been demonstrated in a number of tumor types including thyroid cancer. FAK is regulated on several levels, one of which includes posttranscriptional inhibition by microRNAs among which are miR-7-5p, miR-135a-5p, and miR-138-5p. Changes in the regulation of FAK can disturb its activation and indirectly influence malignant transformation and cancer progression. info:eu-repo/semantics/conferenceProceedings Ignjatović Jocić, Valentina Janković Miljuš, Jelena Išić Denčić, Tijana Živaljević, Vladan Tatić, Svetislav Đorić, Ilona Šelemetjev, Sonja Focal adhesion kinase, microRNA, thyroid tumor http://creativecommons.org/licenses/by/4.0/legalcode Expression of focal adhesion kinase microrna regulators is related to dedifferentiation in thyroid neoplasia spectrum Endocrine Abstracts-45th Annual Meeting of the European Thyroid Association (ETA) 2023 92 https://phaidrabg.bg.ac.rs/o:31257 doi:10.1530/endoabs.92.PS3-28-07 ISSN: 1470-3947 eng Bioscientifica 2023