o:28851 Study on the reactions between dichlorido[2,2´:6´,2´´-terpyridine] zinc(II) and biologically relevant nucleophiles in aqueous solution en Abstract: Substitution reactions of square-pyramidal [ZnCl2(terpy)] complex (terpy = 2,2´:6´,2´´-terpyridine) with biologically relevant nucleophiles such as imidazole, glutathione, 1,2,4-triazole, and pyrazine were investigated at pH 7.0 as a function of nucleophile concentration. The reactions were followed under pseudo first-order conditions by UV-Vis spectrophotometry. The substitution reactions comprised two steps of consecutive displacement of chlorido ligands. Different reaction pathways for the first reaction step of nucleophilic substitution were defined. The order of reactivity of the investigated nucleophiles for the first reaction was Imidazole > glutathione > pyrazine > 1,2,4-triazole, while for the second reaction step it was pyrazine > 1,2,4-triazole > imidazole > glutathione. Keywords: Zinc(II), kinetics, biologically relevant nucleophiles, terpyridine 1552099 10.1177/1468678319825724 1552101 1468-6783 2023-04-18T15:54:58.787Z 44 no 46 Enisa Selimović Državni univerzitet u Novom Pazaru 0000-0002-8212-4378 Tanja Soldatović Državni univerzitet u Novom Pazaru person 0000-0003-3010-6503 application/pdf 491828 https://phaidrabg.bg.ac.rs/o:28851 no yes 1 70 92000001 20A01 Progress in Reaction Kinetics and Mechanism 44 2 105 113 2019