https://phaidrabg.bg.ac.rs/o:28851 doi:10.1177/1468678319825724 ISSN: 1468-6783 All rights reserved Study on the reactions between dichlorido[2,2´:6´,2´´-terpyridine] zinc(II) and biologically relevant nucleophiles in aqueous solution info:eu-repo/semantics/article Keywords: Zinc(II), kinetics, biologically relevant nucleophiles, terpyridine 2019 eng Abstract: Substitution reactions of square-pyramidal [ZnCl2(terpy)] complex (terpy = 2,2´:6´,2´´-terpyridine) with biologically relevant nucleophiles such as imidazole, glutathione, 1,2,4-triazole, and pyrazine were investigated at pH 7.0 as a function of nucleophile concentration. The reactions were followed under pseudo first-order conditions by UV-Vis spectrophotometry. The substitution reactions comprised two steps of consecutive displacement of chlorido ligands. Different reaction pathways for the first reaction step of nucleophilic substitution were defined. The order of reactivity of the investigated nucleophiles for the first reaction was Imidazole > glutathione > pyrazine > 1,2,4-triazole, while for the second reaction step it was pyrazine > 1,2,4-triazole > imidazole > glutathione. Progress in Reaction Kinetics and Mechanism 44(2) Selimović, Enisa Soldatović, Tanja application/pdf 491828 bytes