
<oai_dc:dc xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/">
  <dc:creator>Radenković, Ninko</dc:creator>
  <dc:creator>Kostić, Marina D.</dc:creator>
  <dc:creator id="https://orcid.org/0000-0002-1100-5689">Đorđević, Nataša Z.</dc:creator>
  <dc:creator id="https://orcid.org/0000-0003-0457-3087">Dolićanin, Zana C.</dc:creator>
  <dc:creator id="https://orcid.org/0000-0003-3010-6503">Soldatović, Tanja V.</dc:creator>
  <dc:creator>Živanović, Marko N.</dc:creator>
  <dc:creator>Divac, Vera M.</dc:creator>
  <dc:source>Macedonian Journal of Chemistry and Chemical Engineering 39(1)</dc:source>
  <dc:identifier>https://phaidrabg.bg.ac.rs/o:28849</dc:identifier>
  <dc:identifier>doi:10.20450/mjcce.2020.1905</dc:identifier>
  <dc:identifier>ISSN: 1857-5552</dc:identifier>
  <dc:type>info:eu-repo/semantics/article</dc:type>
  <dc:subject xml:lang="eng">Keywords: organoselenium chemistry; palladium; platinum; cytotoxic activity; colon carcinoma</dc:subject>
  <dc:rights>All rights reserved</dc:rights>
  <dc:description xml:lang="eng">Abstract: Herein we report the synthesis of a new trans-bis(2-phenylselenylmethyl)oxolane)dichloroplati-num(II) complex (Pt1). This newly synthesized complex, together with two structurally related trans-Pd(II) complexes, (trans-bis(2-(phenylselenylmethyl)oxolane) dichloropalladium(II) (Pd1) and trans-bis(2-(phenylselenylmethyl)oxane)dichloropalladium(II) (Pd2), were screened for cytotoxic activity through in vitro studies on the HCT-116 colorectal carcinoma cell line and MRC-5 healthy lung pleura cell line. The activity of the complexes was assessed by comparing it to cisplatin. The cells’ viability and proliferation were determined using an MTT (Microculture Tetrazolium Test) assay. </dc:description>
  <dc:language>eng</dc:language>
  <dc:date>2020</dc:date>
  <dc:format>application/pdf</dc:format>
  <dc:format>1081498 bytes</dc:format>
  <dc:title xml:lang="eng">Synthesis of new Pt(II) complex bearing organoselenium ligands and evaluation of citotoxic activity of some structurally related Pt(II) and Pd(II) complexes</dc:title>
</oai_dc:dc>