o:28429 The comparison of Ocimum basilicum and Levisticum officinale extracts obtained using different extraction solvents and techniques Poređenje ekstrakata vrsta Ocimum basilicum i Levisticum officinale dobijenih primenom različitih ekstrakcionih sredstava i tehnika en ABSTRACT In the present study, basil (Ocimum basilicum L.) and lovage (Levisticum officinale Koch.) extracts were obtained using maceration, ultrasound- and microwave-assisted extractions (UAE and MAE, respectively). Varying the different extraction solvents, including water, methanol, acetone, and ethyl acetate, the analyses of total polyphenol and flavonoid contents (TPC and TFC, respectively), as well as antioxidant properties (DPPH radical scavenging and cupric ion reducing activities) were carried out for all obtained plants’ extracts. The total amount of extractive substances of the selected extracts was also measured. The highest TPC was achieved in water basil extract obtained using UAE, while the highest TFC was determined in the basil extracts prepared using maceration and MAE. The highest level of DPPH radical neutralization was observed for methanol and acetone extracts obtained by maceration (for both plants) as well as UAE and MAE (for lovage). However, the obtained results did not exhibit statistically significant correlation with the TPC and TFC. The highest cupric ion-reducing capacity was measured in methanol lovage extract prepared using UAE and in methanol basil and lovage extracts from MAE. Interestingly, a significantly higher amount of the extractive substances was measured in all methanolic lovage extracts compared to basil parallels. Thus, it can be concluded that the selection of the extraction medium and extraction technique depends on the used plant species, as well as on the future application and purpose (or role) of the prepared extracts. basil, cupric ion reducing antioxidant potential, extraction, lovage, polyphenols 1552099 10.5937/leksir2242043B 1552101 0455-6224 2023-03-28T13:38:36.169Z 44 yes 46 Petar Batinić Institute for Medicinal Plants Research "Dr. Josif Pančić", Belgrade, Serbia Natalija Čutović Institute for Medicinal Plants Research "Dr. Josif Pančić", Belgrade, Serbia person Snežana Mrđan Institute for Medicinal Plants Research "Dr. Josif Pančić", Belgrade, Serbia person Aleksandra A. Jovanović University of Belgrade, Institute for the Application of Nuclear Energy INEP, Serbia doktor biotehničkih nauka person 0000-0001-5394-0125 Katarina Ćirić University of Belgrade, Faculty of Technology and Metallurgy, Serbia person Aleksandar Marinković University of Belgrade, Faculty of Technology and Metallurgy, Serbia person Branko Bugarski University of Belgrade, Faculty of Technology and Metallurgy, Serbia person application/pdf 343858 https://phaidrabg.bg.ac.rs/o:28429 no yes 16 70 92000001 11A29 11A41 Natural medicinal materials 42 Institut za proučavanje lekovitog bilja "Dr. Josif Pančić", Beograd 2022