o:17910 Očuvanje alveolarnog grebena nakon ekstrakcije zuba primenom koštanog morfogenetskog proteina doktorska disertacija Preservation of Alveolar Ridge After Tooth Extraction Using Bone Morphogenetic Protein sr Tokom zarastanja postekstrakcione rane dolazi do značajnih promena alveolarnog grebena koje se mogu podeliti na unutrašnje i spoljašnje promene u zavisnosti koji deo alveoli zahvataju. Unutrašnje promene doprinose zarastanju rane i dovode do formiranja nove kosti u alveoli. Spoljašnje promene su uglavnom resorptivnog karaktera i dovode do gubitka visine i širine alveolarnog grebena, što može dalje otežati ugradnju implantata, kompromitovati protetsko zbrinjavanje pacijenta i estetiku. Do sada korišćeni terapijski pristupi u cilju prevencijere sorptivnih promena i očuvanja alveolarnog grebena, nisu pokazali očekivane rezultate. Preliminarna ispitivanja bioaktivnih supstanci i faktora rasta i njihove primene bi mogla značajno da uspori procese resorpcije idoprinese očuvanju alveolarnog grebena... There are two types of ridge alterations that may affect alveolar socket following tooth extraction: internal and external changes. Internal changes contribute to healing and formation of the new bone in the extraction socket, while external changes are mainly resorptive in nature and cause reduction of width and height of the residual alveolar ridge which can affect positioning of dental implants, make adequate prosthodontics rehabilitation difficult and compromise aesthetics. Previous treatment modalities used to prevent resorptive (external) changes and preserve alveolar ridge failed to obtain satisfactory results. Newly introduced bioactive and growth factors showed promising results and their use could have significant impact in reduction of external resorptive changes after tooth extraction... Tokom zarastanja postekstrakcione rane dolazi do značajnih promena alveolarnog grebena koje se mogu podeliti na unutrašnje i spoljašnje promene u zavisnosti koji deo alveoli zahvataju. Unutrašnje promene doprinose zarastanju rane i dovode do formiranja nove kosti u alveoli. Spoljašnje promene su uglavnom resorptivnog karaktera i dovode do gubitka visine i širine alveolarnog grebena, što može dalje otežati ugradnju implantata, kompromitovati protetsko zbrinjavanje pacijenta i estetiku. Do sada korišćeni terapijski pristupi u cilju prevencijere sorptivnih promena i očuvanja alveolarnog grebena, nisu pokazali očekivane rezultate. Preliminarna ispitivanja bioaktivnih supstanci i faktora rasta i njihove primene bi mogla značajno da uspori procese resorpcije idoprinese očuvanju alveolarnog grebena... There are two types of ridge alterations that may affect alveolar socket following tooth extraction: internal and external changes. Internal changes contribute to healing and formation of the new bone in the extraction socket, while external changes are mainly resorptive in nature and cause reduction of width and height of the residual alveolar ridge which can affect positioning of dental implants, make adequate prosthodontics rehabilitation difficult and compromise aesthetics. Previous treatment modalities used to prevent resorptive (external) changes and preserve alveolar ridge failed to obtain satisfactory results. Newly introduced bioactive and growth factors showed promising results and their use could have significant impact in reduction of external resorptive changes after tooth extraction... ekstrakciona rana, prezervacija, koštanimorfogenetski protein extraction socket, preservation, bone morphogenetic protein yes 38086927 91552101 5901 91552100 38086927 2018-07-17T09:00:00.053Z 45 no 46 mentor Tihana Divnić-Resnik, 1976- 2011 63 mentor Zoran Aleksić 2011 63 član komisije Vojislav Leković 63 član komisije Draginja Kojović Perović 63 član komisije Saša Jaković 218 listova 16090316 http://phaidrabg.bg.ac.rs/o:17910 no yes 4 2018-07-17T09:00:00.320Z 70 1738 11A38 2011