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    <ns1:title language="sr">Faktori rizika za nastanak depresije u adolesceniciji iz ugla Transakcionog stres modela kognitivne vulnerabilnosti</ns1:title>
    <ns2:subtitle language="sr">doktorska disertacija</ns2:subtitle>
    <ns2:alt_title language="en">Risk factors of depression occurrence in adolescence from the perspective of the Cognitive vulnerability - transactional stress model  : doctoral dissertation</ns2:alt_title>
    <ns1:language>sr</ns1:language>
    <ns1:description language="sr">Glavni cilj ove doktorske disertacije je da se ispitaju i utvrde uloge i povezanosti 
faktora   rizika   (kognitivne   vulnerabilnosti,   psihosocijalnih   faktora   rizika,   socio-
demografskih  faktora)  i  klini
č
ke  i  subklini
č
ke  depresije  u  okviru  Transakcionog  stres 
modela  kognitivne  vulnerabilnosti  za  depresiju.
Proverili  smo  i  statisti
č
ki  dokazali 
pretpostavljenu povezanost ovih faktora sa depresijom u adolescenciji. 
 Finalni  uzorak  istra
ž
ivanja 
č
ine  412  adolescenta  (61.7% 
ž
enskog  i  38.3% 
mu
š
kog pola) na uzrastu od 13-17 godina (M=15.70,SD = 1.22). Procedura uzorkovanja 
odvijala  se  u  dve  faze. 
Prva  faza  (pilot  istra
ž
ivanje)
,  za  potrebe  provere  pouzdanosti 
instrumenata sprovedena je na neklini
č
kom uzorku 282 adolescenta na uzrastu od 13-17 
godina,   u 
š
kolama   u   Skoplju.   Instrumenti   su   pokazali   dobre   psihometrijske 
karakteristike. 
U drugoj fazi, u dvogodi
š
njem periodu, 
glavno istra
ž
ivanje je sprovedeno 
u  klinikama  i 
š
kolama  u  tri  glavna  centra  socio-demografskih  regiona  u  Makedoniji 
(
Š
tip, Isto
č
ni region; Skoplje, Centralni region; Bitolj, Zapadni region). Formirane su tri 
grupe: klini
č
ka grupa, subklini
č
ka grupa i kontrolna grupa.  
Finalni  uzorak 
č
ine:  klini
č
ka  grupa,  139  (33.7%)  ispitanika;  subklini
č
ka  grupa, 
133  (32.3  %)  ispitanika  i  140  (34.0%)  ispitanika  u  kontrolnoj  grupi.  Kriterijum  za 
uklju
č
ivanje  u 
klini
č
ki  uzorak
  je  ispunjavanje  dijagnosti
č
kih  kriterijuma 
DSM
-IV-
TR/DSM
-V  (APA,  2000;  2013)  za  unipolarne  depresije  bez  psihoti
č
nih  karakteristika 
(Velika depresija, Major Depression, MDD). Ispitanici iz 
subklini
č
kog uzorka
 imaju cut 
off skor za subklini
č
ku depresiju na BDI II, iznad 16  i ne ispunjavaju kriterijume prema 
M.I.N.I.  kid  intervjuu  za  veliku  depresiju.  Od  preostalih  adolescenata  koji  imaju  niske 
skorove  na  BDI  II,  ispod  cut–off  skora  za  subklini
č
ku  depresiju,  i  pomo
ć
u  skrining 
M.I.N.I. kid intervjua, a na bazi dobijenih podataka iz liste osnovnih podataka, formirali 
smo 
kontrolni uzorak
 adolescenata. Ekskluzivni kriterijumi su bili: prisustvo organskih i 
psihoti
č
nih  poreme
ć
aja; somatske  bolesti;  i  IQ  ispod  75.
Svi  ispitanici  su  popunili  isti 
komplet instrumenata koji smo koristili za ovo istra
ž
ivanje.  
Faktori   kognitivne   vulnerabilnosti   za   depresiju   (disfunkcionalni   stavovi, 
negativan  inferencijalni  stil,  ruminativni  stil  reagovanja),  psihosocijalni  faktori  rizika, 
(negativni 
ž
ivotni  doga
đ
aji  i  percipirana  socijalna  podr
š
ka)  i  socio-demografski  faktori 
(pol, uzrast i 
š
kolski prosek) mereni su pomo
ć
u seta instrumenata. Primenili smo: Listu 
podataka  za  sve  ispitanike;  M.I.N.I.  intervju  (M.I.N.I.  kid  Screen  /  DSM-IV  -  TR/  
Sheehan  &amp;  Lecrubier,  2001/2006);  Skalu  disfunkcionalnih  stavova  (Dysfunctional 
Attitude Scale, DAS; Weissman &amp; Beck, 1978); Upitnik kognitivnog stila adolescenata 
(Adolescent&apos;s  Cognitive  Style  Questionnaire,  ASCQ;  Hankin  &amp;  Abramson,  2002); 
Upitnik  ruminativnog  stila  reagovanja  (Ruminative  Response  Style  Questionnaire, 
RSQ;  Nolen-Hoeksema  &amp;  Morrow,1993);  Upitnik 
ž
ivotnih  doga
đ
aja  adolescenata 
(Adolescent   Life   Events   Questionnaire,   ALEQ;   Hankin   &amp;   Abramson,   2002); 
Multidimenzionalnu  skalu  percipirane  socijalne  podr
š
ke  (Multidimensional  Scale  of 
Perceived  Social  Support,  M
PS
S
; 
Zimet,  Dahlem,  Zimet  &amp;  Farley,1988)  i  Bekovu 
Skalu  depresije  (Beck  Depression  Inventory  II,  BDI-II;  Beck, 
Steer
, 
&amp; 
Brown,1996). 
Statisti
č
ke analize su ra
đ
ene za svaku grupu posebno. 
 Rezultati   istra
ž
ivanja   potvr
đ
uju   da,   u   okviru   Transakcionog   stres   modela 
kognitivne   vulnerabilnosti   depresije   u   adolescenciji,   postoji   zna
č
ajna 
povezanost
izme
đ
u faktora rizika depresije s jedne strane, i nivoa simptoma depresije sa druge. Svi
uklju
č
eni   faktori   rizika   u   modelu   su
jako   me
đ
usobno   povezani   i   imaju   visoku 
interkorelaciju.   Najve
ć
u   korelaciju   (negativna   povezanost)   sa   nivoom   simptoma 
depresije    ima 
percipirana    socijalna    podr
š
ka
,    a    najni
ž
u    korelaciju    (pozitivna 
povezanost)  sa  nivoom  simptoma  depresije  imaju
  negativni 
ž
ivotni  doga
đ
aji  u  domenu 
romanti
č
ne  veze.
  Jedino  pol  i  uzrast  nisu  statisti
č
ki  zna
č
ajno  povezani  sa  nivoom 
simptoma depresije. 
 Potvrdili  smo  i  pretpostavljena  o
č
ekivanja  da  su  faktori  rizika  koji  su  bili 
predmet  na
š
eg  interesa  zna
č
ajni   
prediktori
  nivoa  simptoma  depresije.  Analiza  tri 
prediktivna modela, za sve unesene faktore rizika i za svaku grupu posebno, pokazala je 
da   najve
ć
u   prediktivnu   mo
ć
   ima   model   klini
č
ke   grupe   (90.4%),   zatim   model 
subkl
in
i
č
ke  grupe  (89.5%)  i    model  kontrolne  grupe  (86.8%).  U 
klini
č
koj  grupi
  kao 
najja
č
i  prediktor  iz  grupe  unesenih  faktora  rizika  se  pokazala 
niska  precipirana 
socijalna  podr
š
ka
  koja  predvi
đ
a  vi
š
i  nivo  simptoma  depresije,  a  sa  veoma  nisk
im 
negativnim  vrednostima  bete  je  prediktor 
uzrast. 
Analiza  u 
subklini
č
koj  grupi
je 
pokazala  da,  isto  kao  i  u  klini
č
koj  grupi,  od  grupe  faktora  rizika,  percipirana  socijaln
a 
podr
š
ka  je
najja
č
i  prediktor,  a  najslabiji  je  nizak 
š
kolski  prosek
. 
Za 
kontrolnu  grupu
najja
č
i prediktor je 
negativan inferencijalni stil...</ns1:description>
    <ns1:description language="en">The main objective of this PhD thesis is to investigate and determine the role and 
relationship  of  risk  factors  (cognitive  vulnerability,  psychosocial  risk  factors,  socio-
demographic  factors)  and  clinical  and  subclinical  depression  within  the  Cognitive 
vulnerability-Transactional stress model of  depression.  
We  checked  and  statistically  proven  the  assumed  association  of  these  factors 
with  depression  in  adolescen
ce.
The  final  survey  sample  consists  of  412  adolescents 
(61.7% female and 38.3% male) aged 13-17 years (M = 15.70, SD = 1.22).  
The  sampling  procedure  was  carried  out  in  two  phases. 
The  first  phase  (pilot 
study)
, for the purpose of checking the reliability of the instruments, was conducted on a 
non-clinical sample of 282 adolescent
s,
 between the ages of 13-17 in schools in Skopje. 
The  instruments  showed  good  psychometric  properties
.
In  the  second  phase
, 
in  a  two-
year  period
,  the  main  research  was  conducted  in  clinics  and  schools  in  the  three  main 
centers  of  socio-demographic  regions  in  Macedonia  (Stip,  Eastern  Region,  Skopje, 
Central Region; Bitola, Western Region). Three groups were formed: a clinical group, a 
subclinical group and a control group.  
The  final  sample  consisted  of:  the  clinical  group  139  (33.7%)  respondents;  the 
subclinical group, 133 (32.3%) respondents and 140 (34.0%) respondents in the control 
group.
The  criterion  for  inclusion  in  the  clinical  sample  was  the  fulfillment  of  the 
diagnostic criteria of DSM-IV-TR / DSM-V (APA, 2000; 2013) for unipolar depression 
without psychotic features (Major Depression, MDD). The respondents from 
subclinical 
sample
 have the cut off score for subclinical depression on the BDI II, over 16 and do 
not fulfill the criteria of the MINI kid interview for Major Depression.
Of the remaining 
adolescents  who  have  low  scores  on  BDI  II,  below  the  cut-off  score  for  subclinical 
depression, and by screening with MINI kid interviews, based on the data obtained from 
the list of basic data, we formed a 
control sample
 of adolescents. The exclusive criteria 
were: the presence of organic and psychotic disorders; somatic diseases; and IQ below 
75.
All respondents completed the same set of instruments that we used for this study.  
Cognitive  vulnerability  factors  for  depression  (dysfunctional  attitudes,  negative 
inferential  style,  ruminative  response  style),  psychosocial  risk  factors  (negative  life 
events  and  perceived  social  support)  and  socio-demographic  factors  (gender,  age  and 
school average success) were measured by a set of instruments.
We applied: Data sheet 
for  all  respondents;  M.I.N.I.  Interview  (MINI  kid  Screen  /  DSM-IV  -  TR  /  Sheehan  &amp; 
Lecrubier, 2001/2006); Dysfunctional Attitude Scale (DAS, 
Weis
sman &amp; Beck, 1978); 
Adolescent&apos;s  Cognitive  Style  Questionnaire  (ASCQ,  Hankin  &amp;  Abramson,  2002); 
Ruminative  Response  Style  Questionnaire  (RSQ,  Nolen-Hoeksema  &amp;  Morrow,  1993); 
Adolescent    Life    Events    Questionnaire    (ALEQ,    Hankin    &amp;    Abramson,2002); 
Multidimensional  Scale  of  Perceived  Social  Support  (M
PS
S,  Zimet,  Dahlem,  Zimet  &amp; 
Farley, 1988) and Beck Depression Inventory II ( BD-II, Beck, 1996).  
Statistical analyses were performed for each group separately. The survey results 
confirm that within the Cognitive vulnerability-Transactional stress model of depression 
in  adolescence,  there  is  a  significant  association  between  risk  factors  of  depression  on 
the  one  hand,  and  the  level  of  symptoms  of  depression,  on  the  other.  All  risk  factors 
included  in  the  model  are  strongly  connected  to  each  other  and  have  a  high  inter-
correlation.
The
perceived   social   support
   has   the   highest   correlation   (negative 
correlation)  with  the  level  of  symptoms  of  depression,  and 
negative  life  events  in  the 
domain of romantic relationships 
have the lowest correlation (positive correlation) with 
the  level  of  symptoms  of  depression.  Only  gender  and  age  were  not  significantly 
associated with the level of symptoms of depression. We have also confirmed the presumed expectations that the risk factors that have 
been  the  subject  of  our  interest  are  significant 
predictors 
of  levels  of  depression 
symptoms.
The analysis of the three predictive models for all input risk factors and for 
each  group  separately  showed  that  the  model  of  the  clinical  group  (90.4%)  has  the 
highest  predictive  power,  followed  by  the  model  of  the  subclinical  group  (89.5%)  and 
the model of the control group (86.8%). In the 
clinical group
 the strongest predictor in 
the  group  of  input  risk  factors  is  the 
low  perceived  social  support
  which  anticipates  a 
higher level of depression symptoms, and the predictor
 age
 is with a very low negative 
values of beta.
The analysis of the 
subclinical group
 has shown that, the same as in the 
clinical group, in the group of risk factors, the perceived social support is the strongest 
predictor,  and  the  lowest  is  the  low 
academic  average
.  For  the 
control  group
,  the 
strongest predictor is the 
negative inferential style
...</ns1:description>
    <ns1:description language="sr">Psihologija - Klinička psihologija / Psychology - Clinical psychology   Datum odbrane: 23.10.2015.</ns1:description>
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